cocaine

noun

co·​caine kō-ˈkān How to pronounce cocaine (audio)
ˈkō-ˌkān
: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used especially in the form of its hydrochloride medically as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

Examples of cocaine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
While taking him into custody, cops allegedly found cocaine, heroin, drug paraphernalia and $2,7000 cash inside his car. — Kerry Burke, New York Daily News, 9 Aug. 2026 Irish police said at the time that the ⁠gang had ‌gone from dealing heroin and cocaine in Dublin in the 1990s to operating across Europe. — CNN Money, 9 Aug. 2026 When the emergence of a serial killer targeting teens coincides with the arrival of a new student, Robert Mallory (Homer Gere), suspicion and intrigue (and cocaine) become the name of the game. — Ct Jones, Rolling Stone, 8 Aug. 2026 The staff is full of miscreants, who are snorting lines of cocaine left and right. — Olivia B. Waxman, Time, 7 Aug. 2026 See All Example Sentences for cocaine

Word History

First Known Use

1860, in the meaning defined above

Time Traveler
The first known use of cocaine was in 1860

Phrases Containing cocaine

Rhymes for cocaine

See All Rhymes for cocaine

Browse Nearby Words

coca
cocaine
cocaine family
See all Nearby Words

Cite this Entry

“Cocaine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cocaine. Accessed 17 Aug. 2026.

Copy Citation

Kids Definition

cocaine

noun
co·​caine kō-ˈkān How to pronounce cocaine (audio)
ˈkō-ˌkān
: a bitter habit-forming drug obtained from coca leaves and used in medicine to deaden pain and illegally for its euphoric effects

Medical Definition

cocaine

noun
co·​caine kō-ˈkān, ˈkō-ˌ How to pronounce cocaine (audio)
: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used medically especially in the form of its hydrochloride C17H21NO4·HCl as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

More from Merriam-Webster on cocaine

Nglish: Translation of cocaine for Spanish Speakers

Britannica.com: Encyclopedia article about cocaine

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Popular in Grammar & Usage

See More

A Who’s Who Regarding ‘Who’s’ and ‘Whose’

7 Pairs of Commonly Confused Words

'A' or 'an'? What about before 'h'? An Indefinite Article Guide

Do you 'say your piece' or 'say your peace'?

Why is '-ed' sometimes pronounced at the end of a word?
See More

Popular in Wordplay

See More

Words from the 'Odyssey'

The Longest Long Words List

It's a Scorcher! Words for the Summer Heat

Is “GIF” Pronounced “Jiff” or “Giff”?

12 Lovely and Unusual Words for the Natural World
See More

Popular

See More

A Who’s Who Regarding ‘Who’s’ and ‘Whose’

Words from the 'Odyssey'

The Longest Long Words List
See More

Games & Quizzes

See All
Play Quordle: Guess all four words in a limited number of tries. Each of your guesses must be a real 5-letter word.
Quordle Can you solve 4 words at once?
Play Blossom: Solve today's spelling word game by finding as many words as you can using just 7 letters. Longer words score more points.
Blossom Pick the best words!
Play Missing Letter: a crossword with a twist. Each of the 25 puzzle words start with a different letter of the alphabet. Which letter is missing?
The Missing Letter A daily crossword with a twist
image of a green cube out of place in a lineup of red spheres
Odd Word Out: Synonyms Vol. 2 Quiz Figure out which word isn't like the others.
See All