Synonyms of degradation
1
: the act or process of degrading
environmental degradation
the gradual degradation of organic matter
suffer the degradations of poverty and abuse
2
a
: decline to a low, destitute, or demoralized state
'A dependence upon him,' said Kate, 'would embitter my whole life. I should feel begging a far less degradation.'Charles Dickens
Some houses are found spotless, others in a wretched degradationPaul Reyes
b
: moral or intellectual decadence : degeneration
… educated him in the bestiality and degradation that war brings.Drew Middleton

Examples of degradation in a Sentence

English teachers bemoaning the degradation of the language that e-mail and instant messaging have allegedly brought about. the belief that moral degradation is an unmistakable sign of a nation in decline
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This allows the drug to distinguish cancer cells from healthy cells, directing degradation toward the mutant protein while largely sparing normal tissues. William A. Haseltine, Forbes.com, 6 Aug. 2026 However, its natural habitat is at risk of degradation because of human activities such as aquaculture, conversion of forest and wetlands into farmlands, and infrastructure development. Encyclopedia Britannica, 6 Aug. 2026 These mRNA-lipid nanoparticles, or LNPs, are tiny spheres about 100 nanometers in diameter that protect mRNA from degradation and facilitate its delivery into target cells. Li Li, The Conversation, 6 Aug. 2026 The molecule combined the smallest molecular size among the candidates with superior electrochemical performance, delivering both fast sodium-ion transport and strong stability against degradation at the battery electrodes. Jijo Malayil, Interesting Engineering, 5 Aug. 2026 See All Example Sentences for degradation

Word History

Etymology

see degrade

First Known Use

circa 1535, in the meaning defined at sense 1

Time Traveler
The first known use of degradation was circa 1535

Browse Nearby Words

Cite this Entry

“Degradation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/degradation. Accessed 14 Aug. 2026.

Kids Definition

degradation

noun
1
a
: a reduction in rank, dignity, or standing
b
: removal from office
2
: loss of honor or reputation
3

Medical Definition

degradation

noun
: change of a chemical compound to a less complex compound

More from Merriam-Webster on degradation

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster