: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

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The group distributed them — along with test strips that identify other harmful adulterants, such as fentanyl, xylazine, and medetomidine — at clinics and neighborhood events. Scott Maucione, NPR, 8 Aug. 2026 Mexican authorities have dismantled well over a thousand clandestine drug laboratories, seized enormous quantities of narcotics and fentanyl pills, arrested thousands of cartel operatives, and extradited major criminal figures to the United States. Chris Shays, Hartford Courant, 7 Aug. 2026 An autopsy later showed there was no fentanyl in Williams’ system. Julia Coin august 7, Charlotte Observer, 7 Aug. 2026 Authorities said fentanyl can be sold as pills, with some online dealers claiming the pills are Xanax, Percocet or oxycodone. Rosalio Ahumada, Sacbee.com, 6 Aug. 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 15 Aug. 2026.

Medical Definition

: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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