An overabundance of the SORLA protein protected against a number of biological processes linked to the formation of tau tangles and progression of neurodegeneration.
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Noah Lyons,
San Diego Union-Tribune,
30 July 2026
During this time, the brain starts to shrink, and the misfolded proteins that are a hallmark of Alzheimer’s begin to build up — sticky amyloid beta plaques in the brain and tau tangles in neurons.
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