wakefulness

as in insomnia
the inability to obtain adequate sleep a nagging wakefulness that seemed resistant to all of the standard home remedies

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Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of wakefulness Orexins help regulate wakefulness, as well as attention, motivation and the brain’s reward system. Harriet Marsden, TheWeek, 20 Aug. 2026 But in people with narcolepsy, such boundaries become blurred, allowing elements of sleep to intrude into wakefulness in varying ways. Daryl Austin, USA Today, 8 July 2026 The clinical data demonstrated significant improvements in wakefulness and reductions in excessive daytime sleepiness at week eight, outperforming the placebo with a generally favorable safety profile. Sasirekha Subramanian, Forbes.com, 29 June 2026 Daytime light helps set the body’s circadian rhythms, which play an important role in sleep, wakefulness, and other brain and body functions. Emily Kay Votruba, EverydayHealth.com, 25 June 2026 As a result, many night owls feel groggy in the morning because their bodies have not yet fully prepared for wakefulness. Olivia McIntosh, Martha Stewart, 19 June 2026 That’s followed by periods of contemplation, energized wakefulness, and, purportedly, a vanishing of withdrawal symptoms. Shayla Love, The Atlantic, 24 May 2026 Everybody wants to sound like her, but no one else can quite replicate the particular sonic grammar of her writing, which unfurls like an intimate dispatch from the blurry edge of sleep and wakefulness. New York Times, 28 Apr. 2026 The company’s key asset is cleminorexton (formerly known as ORX750), which seeks to mimic a molecule in the brain, known as orexin, that helps regulate wakefulness. Jeff Marks, CNBC, 31 Mar. 2026
Recent Examples of Synonyms for wakefulness
Noun
  • Orexin antagonists were developed as a treatment for insomnia, differing from conventional sleeping pills that induce sedation.
    Harriet Marsden, TheWeek, 20 Aug. 2026
  • Dozens of other patients described symptoms such as anxiety, acute stress and insomnia, according to the report.
    Los Angeles Times, Los Angeles Times, 20 Aug. 2026
Noun
  • For movement issues, a mattress with better motion isolation can make a partner’s restlessness far less noticeable.
    Ryan Brennan, Charlotte Observer, 20 Aug. 2026
  • Symptoms Symptoms can include sleeplessness, extreme worry about the baby or childbirth, restlessness and a racing heartbeat.
    Jen Christensen, CNN Money, 13 Aug. 2026
Noun
  • During the campaign, candidates are in a state of constant alertness.
    Max Taves, Mercury News, 13 Aug. 2026
  • As evening arrives, the body releases melatonin to signal rest while cortisol, the alertness hormone, drops.
    Samantha Agate, Miami Herald, 8 Aug. 2026

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Cite this Entry

“Wakefulness.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/wakefulness. Accessed 24 Aug. 2026.

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